Roger daltrey 60s6/12/2023 ![]() ![]() There was an awkward transition in between and it took strength to not go to the hairdresser and trim my fringe. Now my hair looks more 70s, simple long straight centre part. I began the year with my signature 60s hairstyle, long, straight (but gets wavy because of the rain), with thick blunt fringe. All we want is to be seen as equals.Ī lot has changed this year. The truth is, female fans are very loyal and are hardcore about their love of classic rock too. Babe of the week, babe of the month? Here’s a better idea: Humans of Classic Rock – like Humans of New York, do listener vox pops and have the listeners tell their stories. I’ve heard many stories from fellow women who love classic rock who get quizzed by older guys whenever they go to concerts or wear band shirts.Īlso doesn’t help when the radio stations try way too hard to have that macho image. When you buy records, sometimes judgemental staff assume it’s a gift for your dad and look puzzled because “how can a young person know about all of this?”. People assume that you’re into classic rock because of your boyfriend/husband or that he’s dragging you to concerts. It’s hard to be a female classic rock fan, especially if you’re a millennial. People know I’m not shallow and they know I love classic rock. I’ve been working on this blog for almost 4 years and I’ve gained a good reputation and following. I think the time is right to write this post. I didn’t want to be dismissed as a silly fangirl who only likes classic rock because the musicians are hot, so I waited. I was a bit worried about writing this post about the best hair in rock (in my opinion). ![]()
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Ivpn service really slow6/12/2023 ![]() ![]() There are two pricing plans for IVPN, which break down into IVPN Standard and IVPN Pro. ![]() (Image credit: IVPN) IVPN price: how much is it, and is there an IVPN free trial? Platforms supported: Windows, Mac, Android, iPhone, iPad, Linux Want to learn more? Just keep reading our full IVPN review for the full breakdown – either by clicking through to a section by using the navigation bar up top, or simply scrolling down. On the downside, IVPN is very poor for streaming with no support to unblock Netflix, Disney Plus, Amazon Prime Video or BBC iPlayer, and it's clear this isn't a priority for the developers. Owned DNS servers are worldwide, adding another layer to that security which means no third-parties are involved as potential weak points. Torrenting is supported across all 45 locations this service spans, which are spread across 32 countries. This is available on its clients for Windows, Mac, iOS, Android and Linux, and with up to 7 devices supported at the same time, IVPN is a compelling choice for groups and families – or those that want VPN security across all their devices at once. The features go beyond security, too, with WireGuard delivering impressive speeds on most of the the service's servers. The end result is a very private and secure service which features on our best VPN guide. ![]() IPVN is a Gibraltar-based VPN provider which is not only in a good placement geographically for security but also uses an independent audit of its no-logging policy. ![]() Tripmode alternative mac6/12/2023 ![]() ![]() This also means that you don’t have to worry about enabling all apps when on your home WiFi, for example. PSA: Dont install macOS 13.4 beta 4 if you use a network filtering app like TripMode. The app even saves your settings based on the respective connection, hence if you’ve enabled it for a mobile data hotspot in the past, Tripmode will be automatically get turned on whenever you connect again to that particular hotspot. In my case, it was merely 30MB on my Windows PC. It’s easy to use: simply enable this smart data blocker app directly in the menu bar and it will be launched anytime your Mac connects to that network. Alternativas a TripMode para todas las plataformas con cualquier licencia Todas las plataformas Cualquier licencia 111 Little Snitch Little Snitch es una aplicación de firewall que monitorea y controla el tráfico saliente de Internet. It automatically reduces your laptop data consumption once you use a mobile hotspot. TCPblock works on system level thus enables to pirated apps work. Tripmode comes with a minimalistic design and lives in the status tray from where you can activate or deactivate it in a couple of clicks. TripMode is the proper mobile data app for you, which offers peace of mind on the go. Tripmode is another app with better and easier interface to block apps from accessing Internet. Furthermore, the app also displays an app-based brief statistic of your data usage in the month or day or a particular session. Tripmode also cuts off your computer’s core components which is one of the major attraction for me due to Windows 10’s aggressive policies. Once installed, Little Snitch monitors your internet traffic and every time it detects an outbound connection, for example, Adobe Reader trying to access the internet, it pops up a window and ask you if you want to allow the connection one time, or make a rule to allow. You can then individually select which apps can access the data and the rest will remain banished until you turn it off. Little Snitch is a popular Mac app that detects outbound connections and lets you set up rules to block those connections. What do you think of TripMode Best alternatives to TripMode Scratch App Promoted Learn more A daily journaling & team check-in system for work and life. If these 3 options don't work for you, we've listed a few more alternatives below. An application for less than 10 that can filter which application can connect to the internet. The best alternatives to TripMode are Polytomic, Bandwidth+, and Samsung Max. Which I dont think anyone ever asked for or expected. But first let me tell you what it does – Tripmode blocks every service or app from using the internet connection your PC or Mac is linked to. On Mac in particular, I had recommended TripMode 2. But he did so after a cute rhetorical question about Apple merging iOS and macOS. Download TripMode for macOS 11.0 or later and enjoy it on your Mac. Tripmode calls itself the “mobile data saviour” and honestly, that is quite true in my personal case. That’s why we recommend installing a tool called “Tripmode”. However, not always, you want these apps to be draining your data and leaving you stranded in the middle of the month. If you have some extra tools you believe it is worth mentioning leave a comment below.With the onset of smarter desktop apps, our internet usage has concurrently elevated at a substantial rate. In case those tools are not essential for your job you can find excellent free alternative solutions, which will save you some money.įinally, if you plan to buy one of the paid applications, always check the official website, since you can find the same item 30% cheaper, due to the cut that Apple takes of sales from Apple store. If you are a professional it is better to pay a trusted company offering a product with support and often updates. ![]() In my opinion for application like Photoshop there is no competitor using open source tools and the same applies to Microsoft Office. Most of the free applications lack some extra features which make the overall experience of the application better. Link: Download – Github Honorable Mentions ![]() Another tool by the developer of LuLu, this one with basic network monitoring functionality and without notifications. ![]() I spit on your grave deja vu6/11/2023 ![]() Lymphedema can be a long-term side effect of some cancer treatments. Because swelling is sometimes a sign of cancer, it is also important to see your doctor to be sure that the cancer has not come back. You will need to learn how to manage the symptoms so they do not get worse. If you develop any symptoms of lymphedema, talk with your doctor as soon as possible. Other times, lymphedema may begin more suddenly. Sometimes the only symptoms may be heaviness or aching in an arm or leg. Symptoms of lymphedema may begin slowly and are not always easy to detect. Nasal congestion or long-lasting middle ear pain, if swelling is severe Thickening and scarring of the skin on the neck and face, called fibrosisĭecreased vision because of swollen eyelidsĭifficulty swallowing, speaking, or breathingĭrooling or loss of food from the mouth while eating Swelling of the eyes, face, lips, neck, or area below the chinĭiscomfort or tightness in any of the affected areasĭifficulty moving the neck, jaw, or shoulders Symptoms of head and neck lymphedema include: Skin that may look like an orange peel (swollen with small indentations) Hardened skin, or skin that does not indent when pressed Rings, watches, or clothes that become too tight People with lymphedema in their arm or leg may have the following symptoms: Lymphedema can occur in people with many types of cancers, including: But it can also happen in the neck, face, mouth, abdomen, groin, or other parts of the body. Or, it may occur months or even years after cancer treatment has ended. Most often, lymphedema affects the arms and legs. Lymphedema may develop immediately after surgery or radiation therapy. But when the lymph nodes are removed or damaged, lymphatic fluid collects in the surrounding tissues and makes them swell. Small glands called lymph nodes filter bacteria and other harmful substances out of this fluid. Lymph travels through the body using a network of thin tubes called vessels. Lymph may also be called lymphatic fluid. Lymph is a colorless fluid containing white blood cells. ![]() ![]() ![]() The lymphatic system helps fight infection and other diseases by carrying lymph throughout the body. Lymphedema is the abnormal buildup of fluid in soft tissue due to a blockage in the lymphatic system. ![]() 3ds sonic racing6/11/2023 ![]() ![]() While Sonic agrees with his friends that the situation seems sketchy, Sonic is curious to test out these super cars and convinces his friends to join him by promising them that nothing bad can happen as long as he is around. Knuckles himself does not trust Dodon Pa either. Not satisfied with Dodon Pa's answer, Amy notices that Dodon Pa's manner of speaking is suspiciously Eggman-esque. He explains to them, in a condescending and vague manner, that he wants them to test the most technologically advanced racing vehicles ever built on his perilous custom circuits in a Grand Prix where teamwork is the key. ![]() Soon after, an enigmatic stranger approached, a Tanuki calling himself Dodon Pa. After Sonic explains their reasons for coming, Amy remarks that Team Rose did not get any invitations. There, they come across Amy, Big and Omochao, who are having a picnic. When Team Sonic receives a vaguely worded invitation to the Ultimate Test of Racing Skill, curiosity soon gets the better of Sonic, Knuckles and Tails, who make a beeline for the rendezvous at the beach. Sonic upon receiving his mysterious invitation. Spoiler warning: Plot, ending details or any kind of information follow.
Breaded fish fillets in air fryer6/11/2023 ![]() ![]() Full of good and simple ingredients, this is an easy recipe to whip up in a pinch! This Salmon Patties with Spring Salad is super easy to make and only takes a couple minutes to put together. Salmon patties in air fryerĬrispy salmon croquettes don’t have to be made in the pan or oven! They are delicious from the Air Fryer too. Air fryer mahi mahiĪir Fryer Baja Mahi Mahi Fish Tacos are absolutely the best. It’s the perfect keto dinner with fresh flavors. Learn how to make air fryer cod with this easy recipe using lemon and simple spices for a tender, delicate and delicious cod fish dinner in under 20 minutes.Īn easy light air fryer cod recipe with lemon and dill made with no breading. Fish steaks are airfried and added to the curry base. This air fryer version has a flavorful coating and can be paired with your favorite white fish such as cod.ĭelicious Indian fish curry recipe with robust flavors. Skip the carryout and make your own fried fish at home. Air fryer catfishĮasy Southern style fried catfish in the air fryer! Crunchy crust with tender flaky fish inside! Cod in air fryer The citrus and Parmesan cheese crust gives the tilapia that perfect crunch, making for the best fish and chips.ĭelightful breaded tilapia fillets. Tilapia cooked to perfection in the air fryer. You can cook perfect tilapia in your air fryer in only 10 minutes! These crispy homemade air fryer fish sticks have just 6 ingredients including the fish! The recipe is gluten-free and eggless too with an easy dijon remoulade sauce for serving. A kids’ favorite, they are a perfect dinner option for busy families. They cook up so much crispier than baked fish sticks and are healthier than deep frying. If you love crunchy battered fish, you will love these Air Fryer fish sticks. Perfect for a quick weeknight dinner! Fish sticks in air fryer This recipe for Air Fryer Salmon will help you get crispy, tender and flavorful salmon in less than 20 minutes. There are so many ways to make it and any kind of fish turns out great! Ninja foodi salmon It’s an amazing way to get a crispy outside and a juicy inside on your fish. Here is the one I have:įish turns out so tender and flaky in the air fryer. There are so many wonderful things you can make in it. The Ninja Foodi air fryer oven has been a game-changer in my kitchen and my life. You can read all the recipe details are in the recipe box below.I am pretty new to learning how to cook fish, but my Ninja Foodi air fryer oven has been a game-changer for me to create some air fryer fish recipes that you’re going to love! I love all the Ninja Foodi Air Fryer Recipes I’m learning to make.This will ensure that it doesn’t come off the fish before you air fry it. Careful! Be gentle when dipping the fish into the egg and breading.Set your eggs and bread crumbs ready to go. Slice your fresh fish into about 2″ wide strips or you can leave it as whole fillets. ![]() ![]() Prep your fresh fish by blotting it dry of all moisture, If you’re using frozen fresh fish, thaw it completely and then dry it out excess water. ![]()
Chalice dungeon best glyphs mini bosses6/11/2023 ![]() Kill the Brain of Mensis in Nightmare of Mensis to obtain Living String (another raw material for opening chalice dungeons).Defeat Ebrietas to obtain Great Isz Chalice.Defeat Amygdala in Nightmare Frontier to obtain Ailing Loran Chalice (collect 4x Coldblood Flowerbuds in Nightmare Frontier for opening more chalice dungeons).Complete Pthumeru Chalice, Central Pthumeru Chalice & Lower Pthumeru Chalice (don't remove this dungeon after completion as you can farm Ritual Blood (4) here).Defeat the Blood-starved Beast to obtain Pthumeru Chalice.Obtain 2x Ritual Blood (1) from altar near the hanging beast in the big hall in Old Yharnam."If you don't meet the requirements to join certain chalice dungeons" I would highly recommend using this technique for blood stone chunks farming after you've killed Brador in the jail cell corridor so that both enemies (staff guy & wheelchair huntsman) will be dead & will not cause issues when running back & forth between the Research Hall & Nightmare Church lamps.ģ.DON'T die during this process or you will lose your progress of killing Wandering Nightmares & will have to start the entire process again.This works only ONCE every playthrough so you may want to spend some time doing it to get as many blood stone chunks as possible.75min of doing this gave me about 140 blood stone chunks.You will keep getting the option to "search the corpse." Keep doing that until you don't see it anymore. When you feel you've farmed enough then loot the Wandering Nightmares after killing them. Run back to the Research Halls & kill the two Wandering Nightmares again but again DO NOT loot them ! Repeat this process & remember NOT to loot the Wandering Nightmares. Kill the Wandering Nightmare but DO NOT loot it. Run back to the Nightmare Church lamp & down the staircase. Run to the far end of the hall (across the poisonous water) & you will see another Wandering Nightmare on the steps. Kill the Wandering Nightmare on your left but DO NOT loot it. Run up the steps next to the lamp & you will enter a large hall with a spiral staircase. You need to be at the Research Halls lamp to make this work. ![]() Follow Kekimus Prime's Guide to farm as many blood stone chunks as you want.Note: You need to own the DLC (works on Patch v1.09).Blood Stone Chunks Farming (Kekimus Prime's Method) Mob Enemies through Central Yharnam = Blood Vials & Quicksilver Bullets.Ģ.Huntsmen (Rifle) & Wheelchair Huntsmen = Quicksilver Bullets.Scourge Beasts, Large Huntsmen & Huntsman Minions = Blood Vials.Blood Vials & Quicksilver Bullets Farming Tip: Regularly upload your Bloodborne save file (a valid PS+ subscription is needed):.The Easy Farming Guide for all things Bloodborne (2018) by asim_rizīlood Vials, QS Bullets, Upgrade Material, & Blood Echoes ![]()
Crift 2015 deep therapy6/11/2023 ![]() ![]() Local recurrence after surgery is a persistent problem, occurring in 5–40% cases. It has the advantage of relieving symptoms in 60–90% of patients, achieving local control in 60–100%, and enabling diagnostic testing for biomolecular markers, which may differ from the primary tumor for example, expression of therapeutically targetable receptors for estrogen, progesterone and/or epidermal growth factor (ER/PR/HER2) is discordant in 20–50% of breast cancer cases. Surgery is most valuable for symptomatic lesions that are accessible, in patients with controlled extracranial disease and good performance status. For example, HER2+ breast cancer patients with isolated brain metastases or synchronous but stable extracranial disease may live 5 years or more with multi-modal treatment, while those with triple-negative breast cancer (TNBC), non-small cell lung carcinoma (NSCLC) and melanoma typically succumb within 12 months, even with aggressive treatment. ![]() However, clinical outcomes vary considerably depending on primary cancer histology, comorbidities and the extent of metastatic disease elsewhere in the body. Based on the widely-utilized Graded Prognostic Assessment (GPA) prognostic index, the median survival of patients with brain metastases is 7.16 months. Depending on the number, sizes and location of lesions, age and general health, management may involve surgical resection, stereotactic or whole brain irradiation, with long-term steroid treatment to limit intracranial edema. The aims of this review are to outline conventional management strategies ( Section 2), pathophysiological and molecular factors that underpin the recalcitrance of brain metastases ( Section 3) and review new approaches to systemic therapy where compelling preclinical and/or clinical evidence indicates they could play a role in clinical management in the future.īrain metastases are usually diagnosed by magnetic resonance imaging (MRI) in patients who present with neurological symptoms, such as headache, cognitive deficits or seizures. Consistent with this, adjuvant treatment of human epidermal growth factor receptor-2 positive (HER2+) breast cancer with the anti-HER2 monoclonal antibody (mAb) trastuzumab (Herceptin ®) increases the likelihood that the brain will be the first site of symptomatic recurrence. In addition to population ageing, and improvements in the precision and accessibility of diagnostic imaging, this trend is also thought be a consequence of contemporary systemic drug therapies that are more effective against extracranial that intracranial cancer deposits. The risk of brain relapse for cancer patients today is higher than it was several decades ago. Solving these long-standing challenges around diagnosis and treatment requires innovation. They are broadly refractory to existing systemic therapies because of inefficient drug delivery, unique brain growth factors that promote resistance, and because they are usually detected at a late stage, when patients are already symptomatic. Brain metastases occur in 9–17% of cancer patients, most frequently in melanoma, lung and breast cancer. The spread of cancer to the brain is a devastating complication associated with high morbidity and virtually 100% mortality. Here, we discuss molecular and physiological factors that contribute to the recalcitrance of these tumors, and review emerging therapeutic strategies, including agents targeting the PI3K axis, immunotherapies, nanomedicines and MRI-guided focused ultrasound for externally controlling drug delivery. New strategies must account for resistance mechanisms that are frequently engaged in this milieu, such as HER3 and other receptor tyrosine kinases that become induced and activated in the brain microenvironment. Brain metastases are also highly adapted to their microenvironment, with complex cross-talk between the tumor, the stroma and the neural compartments driving speciation and drug resistance. For example, heterogeneous permeability, abnormal perfusion and high interstitial pressure oppose the conventional convective delivery of circulating drugs, thus new delivery strategies are needed to achieve uniform drug uptake at therapeutic concentrations. The factors limiting intracranial efficacy of existing agents are both physiological and molecular in nature. Notwithstanding improvements in the precision and efficacy of these life-prolonging treatments, with no reliable options for adjunct systemic therapy, brain recurrences are virtually inevitable. ![]() This has been the case for decades, largely because we lack effective therapeutics to augment surgery and radiotherapy. They are associated with a very poor prognosis and near 100% mortality. Brain metastases are the most prevalent of intracranial malignancies. ![]() Time zones in russia6/11/2023 ![]() ![]() ![]() Uses the closest city, rather than the more common Eastern,Ĭentral, Mountain or Pacific time zones in the United States. Rayevskiy on the map Location: Bashkortostan, Rssia Latitude: 54.066. Seconds announced at irregular intervals to compensate for theĮarth's slowing rotation. Compare other time zones Sunrise, sunset, day length and solar time for Rayevskiy Nascer do sol: 05:22 Pr do sol: 21:11 Durao do dia: 15h 48m Solar noon: 13:17 The current local time in Rayevskiy is 77 minutos ahead of apparent solar time. Seconds defined by International Atomic Time (TAI), with leap Time (UTC), or Greenwich Mean Time (GMT). Positive or negative offset computed from Coordinated Universal Use it as a meeting planner or a scheduler to find the best time The calculator will automaticallyĪdjust for daylight saving time (DST) in the summer. You can enter airports,Ĭities, states, countries, or zip codes to find the time differenceīetween any two locations. This is the best time to reach them fromĬonverter for places all over the world. ![]() This will be between 7AM - 11PM their time, since United States is 13 hours behind Russia.īut you want to reach someone in United States at work, you may want to try between 10:00 PM and 6:00 AM your time. If you live in Russia and you want to call a friend in United States, you can try calling them between 8:00 PM and 12:00 PM your time. Schedule a phone call from Russia to United States That will end up being between 6:00 PM and 7:00 PM in United States. Meeting at the best time for both parties, you should try between 7:00 AM and 8:00 AM your time in Russia. With the meeting planner is to expand the range to cover from 7:00 AM to 7:00 PM your time (Russia). Unfortunately, there aren't any times that overlapīetween your normal working hours and theirs. Meeting planner for Russia and United States ![]() Mushroom squish mellow6/11/2023 ![]() ![]() Zodiac enthusiasts and Astrologers love this spooky squishy. In her leisure, she enjoys studying astrology because she wants to be an astrologer when she grows up. As a bat, it’s a no-brainer that Emily was part of the Halloween Squad.Įmily has an older brother Bart, but she’s a loner. What says spooky like pumpkins and black bats? Exactly. Emily the Bat in Pumpkin Squishdate: 2021 (Available) Collector No.: – Squad: Halloween Size: 3.5”, 5”, 8”, 12”, 16” Price: $352.50 The success of the pink seahorse led to an updated design with more sizes since the OG Sheldon came in limited 3.5 and 7-inches sizes. Sheldon has a pink model released earlier than the teal color, but it’s not as rare. He studies his surroundings, including all the organisms living in the ocean with him. Like the movie character in The Big Bang Theory, Sheldon is curious. He, too, wanted to become a Jellyfish, but he got stuck being a Seahorse. If you’ve ever considered being someone else or identity crisis, then you have a pal in Sheldon the Blue Seahorse. Sheldon the Blue Seahorse Squishdate: Collector No.: 346 Squad: Summer Fun / Fantasy Size: All Sizes, Stackable Price: $350 Please note that only the 16-inch Belana wears a paisley print mint green scarf, as seen in the picture above. Together the siblings make a formidable team with Ronnie making furniture and Belana painting them. Belana isn’t alone in the world though she has a brother Ronnie. Her creativity and interest in art endeared her to collectors immediately making her sell out fast. Belana the Cow Squishdate: Collector No.: 579 Squad: Easter Size: 3.5”, 5”, 8”, 12”, 16”, Stackable Price: $350īelana may be one of the newest additions to the fold but she hit the ground running. Here’s a list of the highest-selling rare Squishmallows on eBay in the past year. Each one has a unique trait and its name on its hangtag, making them relatable to collectors. Once you begin collecting, we believe you’ll understand why it’s called a Squishmallow – words alone can’t do it justice. Of course, every business hopes for success, but you can be sure that Kelly Toy’s didn’t expect a 21st-century Beanie Babies craze-style success. When Kelly Toy started the line in 2017, the company had no idea that its Squishmallows would blow up four years later. There are different sizes, from small 2-inches squishy toys to big 24-inches cuddle buddies. How many different Squishmallows are there?Ī Squishmallow is a stuffed toy made of soft materials in different characters.15 Rarest and Most Valuable Squishmallows.Try one for the first time or build your personal collection by picking out the perfect plush pet.Who Is Malcolm The Mushroom? Have you ever met a soccer-playing Mushroom? Malcolm is the one for you! He’s the goalie on his team and they’ve won the championship three years in a row!FeaturesSoft and cuddly SquishmallowsMeasures 16 inches tall / 40. No matter which creature comfort you desire from our selection of squishy pals, you'll be sleeping better or feeling more relaxed and calm in no time! Soft and plushy toys are known to aid in decreasing stress and anxiety, especially for children suffering from emotional disorders. Super Soft and Super Popular! Get in on the cuddly craze that's sweeping the nation! Squishmallows plush toys are the hottest characters around, whether you're a collector or just need a soft friend to hug and to hold. ![]() |